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cameo¶
cameo is a python library for computer-aided metabolic engineering and optimization of microbes. It caters to different audiences as it provides a high-level interface that allows computer savvy bench biologists to predict heterologous pathways and enumerate engineering strategies and a modular framework for computational modelers that facilitates methods development and the construction of custom analysis workflows and prediction tools.
cameo is based on cobrapy, the community standard for constraint-based modeling of genome-scale metabolic models, and uses and extends the same data structures. For efficiency reasons, however, it differs quite significantly from cobrapy in the way optimization problems are solved and defined. Nevertheless, cameo models remain 100% compatible with cobrapy. If you are already a cobrapy user you might want to start reading here to get an overview of the main differences.